HFE Monoclonal Antibody - BT-MCA0673

HFE Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0673-50, BT-MCA0673-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Research Areas: Signal transduction; Stem cells; Metabolism

Target Protein: HFE

Applications: WB, IF, ICC, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Hereditary hemochromatosis protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q30201; Mouse: P70387

Synonyms: HFE; HLAH; Hereditary hemochromatosis protein; HLA-H

GeneID: Human: 3077

Research Use Only