HFE Monoclonal Antibody - BT-MCA3185

HFE Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3185-50, BT-MCA3185-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Research Areas: Signal transduction, Stem cells, Metabolism

Target Protein: HFE

Applications: ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3F1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: HFE

Immunogen: Purified recombinant fragment of human HFE expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 40kDa

UniProt Accession: Q30201

Synonyms: HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790, dJ221C16.10.1

GeneID: 3077

Research Use Only