Product Description

Histone H2A Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11028-50, MB11028-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P04912

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Histone H2A in K562, C6Lysates using Histone H2A antibody.

Bioworld Molecular Weight: Calculated MW: 14 kDa; Observed MW: 14 kDa

Specificity: IgG

Alternative Name: Histone H2A.2

Immunogen: A synthetic peptide of Histone H2A

Conjugate: Unconjugated

Modification: Unmodified