Product Description

Histone H4 (Acetyl-K91) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS74035-50, BS74035-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Other (Wide Range)

Host: Rabbit

Applications: WB, IF

Alternate Names: FO108, H4, H4/n, H4F2, H4FN, HIST2H4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Acetylated

Immunogen: A synthetic Peptide of human Acetyl-Histone H4-K91

Dilution: WB 1:500 - 1:2000 IF 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Histone H4 (Acetyl-K91) polyclonal antibody detects endogenous levels of Histone H4 protein only when acetylated at Lys91.

Molecular Weight: Refer to figures

Pathway: Examples of Crosstalk Between Post-translational Modifications,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P62805

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only