HK1 Monoclonal Antibody - BT-MCA2322

HK1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2322-50, BT-MCA2322-100

Citations, Manuals and MSDS Available upon request.

Background: The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

Research Areas: Cardiovascular

Target Protein: HK1

Applications: WB, IHC, ICC

Reactivity: Human, Rat, Mouse

Clonality: Monoclonal

Clone ID: 7A7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: HK1

Immunogen: Purified recombinant fragment of human HK1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 102kDa

UniProt Accession: P19367

Synonyms: HKI, HXK1, HK1-ta, HK1-tb, HK1-tc, HK1

GeneID: 3098

Research Use Only