Product Description

HLA-DMB Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS79061-50, BS79061-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecμle is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellμlar vesicles. DM plays a central role in the peptide loading of MHC class II molecμles by helping to release the CLIP (class II-associated invariant chain peptide) molecμle from the peptide binding site. Class II molecμles are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellμlar domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: HLA-DMB, D6S221E, RING7, major histocompatibility complex, class II, DM beta

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human HLA-DMB(NP_002109.2).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 29kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P28068

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only