HLA-DPA1 Monoclonal Antibody - BT-MCA3755

HLA-DPA1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3755-50, BT-MCA3755-100

Citations, Manuals and MSDS Available upon request.

Background: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Research Areas: Others

Target Protein: HLA-DPA1

Applications: WB, IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2B1A10

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: HLA-DPA1

Immunogen: Purified recombinant fragment of human HLA-DPA1 (AA: 29-209) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 29.3kDa

UniProt Accession: P20036

Synonyms: DPA1, PLT1, HLADP, HLASB, DP(W3), DP(W4), HLA-DPA, HLA-DP1A, HLA-DPB1

GeneID: 3113

Research Use Only