HMG-1 Polyclonal Antibody - BT-AP04141

HMG-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04141-20, BT-AP04141-50, BT-AP04141-100

Citations, Manuals and MSDS Available upon request.

Background: HMGB1 encodes high mobility group box 1 that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: HMGB1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: HMG-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 24894

UniProt Accession: Human: P09429; Mouse: P63158; Rat: P63159

Synonyms: HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1

GeneID: Human: 3146; Mouse: 100862258; Rat: 25459

Research Use Only