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HMGCS2 Rabbit pAb - A14244

HMGCS2 Rabbit pAb - A14244

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HMGCS2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A14244-20, A14244-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, IF-P, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 57kDa

Observed Molecular Weight: 50kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 3158

SWISS: P54868

Alternate Names: HMGCS2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:2000 - 1:8000 IF-P, 1:50 - 1:100 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Lipid Metabolism, Cholesterol Metabolism, Cardiovascular, Lipids.

NCBI Alias: HMGCS2

Research Use Only