HNF1B Monoclonal Antibody - BT-MCA4024

HNF1B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4024-50, BT-MCA4024-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: HNF1B

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Mouse, Rat

Clonality: Monoclonal

Clone ID: 4H5C7

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: HNF1B

Immunogen: Purified recombinant fragment of human HNF1B (AA: 23-132) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 61.3kDa

UniProt Accession: P35680

Synonyms: T2D, FJHN, HNF2, LFB3, RCAD, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, ADTKD3, HNF-1B, HNF1beta, HNF-1-beta

GeneID: 6928

Research Use Only