Product Description

HNF4A Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-64889-60, E-AB-64889-120, E-AB-64889-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HNF4A

Target Synonym: HNF4A; FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Developmental Biology, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P41235

Background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human HNF4A (NP_000448.3).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 43-56kDa

Observed MW: 57kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only