hnRNP DL Polyclonal Antibody - BT-AP04171

hnRNP DL Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04171-20, BT-AP04171-50, BT-AP04171-100

Citations, Manuals and MSDS Available upon request.

Background: HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by HNRNPDL has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for HNRNPDL. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by HNRNPDL are similar to its family member HNRPD.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: HNRPDL

Applications: IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: hnRNP DL Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 46438

UniProt Accession: Human: O14979; Mouse: Q9Z130; Rat: Q3SWU3

Synonyms: HNRPDL; JKTBP; Heterogeneous nuclear ribonucleoprotein D-like; hnRNP D-like; hnRNP DL; AU-rich element RNA-binding factor; JKT41-binding protein; Protein laAUF1

GeneID: Human: 9987; Rat: 305178

Research Use Only