hnRNP U Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A3917-20, A3917-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14.
Synonyms: SAFA; DEE54; HNRPU; SAF-A; U21.1; pp120; EIEE54; GRIP120; hnRNP U; HNRNPU-AS1
GeneID: 3192
Swiss-Prot: Q00839
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 91kDa
Observed Molecular Weight: 120kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 608-825 of human hnRNP U (NP_114032.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC, IP
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200 | IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Research Areas: Epigenetics Nuclear Signaling, RNA Binding
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: A431, Jurkat, OVCAR3
Cellular Location: Cell surface, Cytoplasm, Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.