HPRT Monoclonal Antibody - BT-MCA0734

HPRT Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0734-50, BT-MCA0734-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

Research Areas: Epigenetics and nuclear signaling; Cell biology

Target Protein: HPRT1

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Hypoxanthine-guanine phosphoribosyltransferase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P00492; Mouse: P00493

Synonyms: HPRT1; HPRT; Hypoxanthine-guanine phosphoribosyltransferase; HGPRT; HGPRTase

GeneID: Human: 3251

Research Use Only