HRI Polyclonal Antibody - BT-AP04212

HRI Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04212-20, BT-AP04212-50, BT-AP04212-100

Citations, Manuals and MSDS Available upon request.

Background: Eukaryotic translation initiation factor 2-alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Others

Target Protein: EIF2AK1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: HRI Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 71106

UniProt Accession: Human: Q9BQI3; Mouse: Q9Z2R9

Synonyms: EIF2AK1; HRI; KIAA1369; Eukaryotic translation initiation factor 2-alpha kinase 1; Heme-controlled repressor; HCR; Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; Heme-regulated inhibi

GeneID: Human: 27102; Mouse: 15467

Research Use Only