Product Description

HSF2B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES15599-50, ES15599-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human HSF2B AA range: 201-251

Isotype: IgG

Target: HSF2B

Specificity: This antibody detects endogenous levels of HSF2B at Human

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Testis specific, Overexpressed in some tumors (PubMed:31242413),

Molecular Weight (Da): 37kD

Function: Function: May be involved in modulating HSF2 activation in testis
PTM: Sumoylated by UBE2I in response to MEKK1-mediated stimuli
Subunit: Associates with HSF2. The interaction seems to occur between the trimerization domain of HSF2 and the N-terminal hydrophilic region of HSF2BP
Tissue Specificity: Testis specific

Subcellular Location: Cytoplasm Chromosome Localizes on double-strand breaks (DSBs) in mitotic and meiotic chromosomes

Storage and Stability: -20°C/1 year

Gene Name: HSF2BP

Protein Name: HSF2B

Research Use Only