HXK I Monoclonal Antibody - BT-MCA0758

HXK I Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0758-50, BT-MCA0758-100

Citations, Manuals and MSDS Available upon request.

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Research Areas: Signal transduction; Cancer; Metabolism; Cardiovascular

Target Protein: HK1

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Reactivity: Human,Mouse,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Hexokinase-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P19367; Mouse: P17710; Rat: P05708

Synonyms: HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I

GeneID: Human: 309825058

Research Use Only