HXK II Monoclonal Antibody - BT-MCA0761

HXK II Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0761-50, BT-MCA0761-100

Citations, Manuals and MSDS Available upon request.

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Research Areas: Signal transduction; Cancer; Metabolism; Cardiovascular

Target Protein: HK2

Applications: WB

Reactivity: Human,Mouse,Rat,Pig

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Hexokinase-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P52789; Mouse: O08528; Rat: P27881

Synonyms: HK2; Hexokinase-2; Hexokinase type II; HK II; Muscle form hexokinase

GeneID: Human: 3099; Mouse: 15277; Rat: 25059

Research Use Only