I Kappa B- Alpha Monoclonal Antibody - BT-MCA0792

I Kappa B- Alpha Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0792-50, BT-MCA0792-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Research Areas: Signal transduction; Neuroscience; Epigenetics and nuclear signaling; Cancer; Stem cells

Target Protein: NFKBIA

Applications: WB

Reactivity: Human,Mouse,Rat,Pig,sheep

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: NF-kappa-B inhibitor alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P25963; Mouse: Q9Z1E3; Rat: Q63746

Synonyms: NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3

GeneID: Human: 4792; Mouse: 18035; Rat: 25493

Research Use Only