Product Description

IAPP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS78388-50, BS78388-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P10997

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC, IF/ICC

All Applications: IHC,1:50 - 1:200 | IF/ICC,1:50 - 1:200

Background: This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry of paraffin-embedded Rat pancreas using IAPP Rabbit pAb at dilution of 1:100. Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol., Immunohistochemistry of paraffin-embedded Mouse pancreas using IAPP Rabbit pAb at dilution of 1:100. Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol., Immunofluorescence analysis of rat pancreas using IAPP antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of mouse pancreas using IAPP antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Alternative Name: IAPP; DAP; IAP

Immunogen: A synthetic peptide of human IAPP(NP_000406.1).

Conjugate: Unconjugated

Modification: Unmodified