ICAM1 Monoclonal Antibody - BT-MCA2619

ICAM1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2619-50, BT-MCA2619-100

Citations, Manuals and MSDS Available upon request.

Background: ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

Research Areas: Immunology

Target Protein: ICAM1

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6G12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ICAM1

Immunogen: Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 57.8kDa

UniProt Accession: P05362

Synonyms: BB2, CD54, P3.58, ICAM1

GeneID: 3383

Research Use Only