Product Description

IDUA Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18101-60, E-AB-18101-120, E-AB-18101-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: IDUA

Target Synonym: Alpha L iduronidase; IDA; Iduronidase alpha L; MPS1

Research Areas: Metabolism, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P35475

Background: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Concentration: 0.96 mg/mL

Immunogen: Synthetic peptide of human IDUA

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only