IFN-gamma Monoclonal Antibody - BT-MCA3038

IFN-gamma Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3038-50, BT-MCA3038-100

Citations, Manuals and MSDS Available upon request.

Background: Interferon-G (IFN-G) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-G strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB

Research Areas: Others

Target Protein: IFN-gamma

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3F1E3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: IFN-gamma

Immunogen: Purified recombinant fragment of human IFN-γ expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS containing 0.03% sodium azide.

Molecular Weight (Da): 19.3kDa

UniProt Accession: P01579

Synonyms: IFG, IFI

GeneID: 3458

Research Use Only