IFT74 Polyclonal Antibody - E-AB-64297

IFT74 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-64297-60, E-AB-64297-120, E-AB-64297-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: IFT74

Target Synonym: IFT74; BBS20; CCDC2; CMG-1; CMG1

Research Areas: Cancer, Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96LB3

Background: Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human IFT74 (NP_001092694.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:3000

Calculated MW: 42kDa/69kDa

Observed MW: 80kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only