IGFBP2 Monoclonal Antibody - BT-MCA3501

IGFBP2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3501-50, BT-MCA3501-100

Citations, Manuals and MSDS Available upon request.

Background: IGFBP2: insulin-like growth factor binding protein 2. IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Research Areas: Signal transduction, Cancer

Target Protein: IGFBP2

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1F6F6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: IGFBP2

Immunogen: Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P18065

Synonyms: IBP2, IGF-BP53

GeneID: 3485

Research Use Only