IGLL1 Polyclonal Antibody - E-AB-19173

IGLL1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19173-60, E-AB-19173-120, E-AB-19173-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: IGLL1

Target Synonym: 14.1; AGM2; CD179 antigen-like family member B; CD179b; CD179b antigen; Ig lambda 5; Ig lambda-5; IGL1; IGL5; IGLJ14.1; IGLL; Igll1; IGLL1; IGO; IGVPB; Immunoglobulin lambda like polypeptide 1 precursor; Immunoglobulin lambda-like polypeptide 1; Immunoglobulin omega polypeptide; Immunoglobulin omega polypeptide chain; Immunoglobulin related protein 14.1; Immunoglobulin-related protein 14.1; Lambda5; Pre B lymphocyte specific protein 2; VPREB2

Research Areas: Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P15814

Background: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.IGLL1 (Immunoglobulin Lambda Like Polypeptide 1) is a Protein Coding gene. Diseases associated with IGLL1 include Agammaglobulinemia 2 and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Cell surface interactions at the vascular wall and Primary immunodeficiency. An important paralog of this gene is IGLL5.

Concentration: 1.14 mg/mL

Immunogen: Fusion protein of human IGLL1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only