IkB alpha Polyclonal Antibody - E-AB-40093

IkB alpha Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-40093-60, E-AB-40093-120, E-AB-40093-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NFKBIA

Target Synonym: I kappa B alpha; I-kappa-B-alpha; IkappaBalpha; IkB-alpha; IKBA; IKBA; IKBalpha; MAD 3; MAD3; NF kappa B inhibitor alpha; NFKBI; IKB alpha

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q63746

Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Concentration: 2mg/mL

Immunogen: Recombinant Rat NF-kappa-B inhibitor alpha protein

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only