IL-1α (F8) Polyclonal Antibody-BS2825

IL-1α (F8) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2825-50, BS2825-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01583

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of IL-1α (F8) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 17 kDa

Specificity: IL-1α (F8) polyclonal antibody detects endogenous levels of IL-1α protein

Alternative Name: Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A; IL1F1

Immunogen: Synthetic peptide, corresponding to amino acids 91-140 of Human IL-1α.

Conjugate: Unconjugated

Modification: Unmodified