IL-1 Alpha Monoclonal Antibody - BT-MCA0767

IL-1 Alpha Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0767-50, BT-MCA0767-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Research Areas: Immunology; Metabolism

Target Protein: IL1A

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Interleukin-1 alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P01583; Mouse: P01582

Synonyms: IL1A; IL1F1; Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1

GeneID: Human: 3552

Research Use Only