IL-17 Receptor C Polyclonal Antibody-BZ16444

IL-17 Receptor C Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16444-50, BZ16444-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q8NAC3

Host: Rabbit

Reactivity: Human

Applications: WB, ELISA

All Applications: WB: 1/500-1/1000 ELISA: 1/10000

Background: This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 86 kDa; Observed MW: 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of IL-17 Receptor C in various lysates using IL-17 Receptor C antibody., Western blot analysis of IL-17 Receptor C in HuvEc lysates using IL-17RC antibody., Western blot analysis of IL-17 Receptor C in RAW264.7 lysates using IL-17RC antibody.

Alternative Name: IL17RC; Interleukin-17 receptor C; IL-17 receptor C; IL-17RC; Interleukin-17 receptor homolog; IL17Rhom; Interleukin-17 receptor-like protein; IL-17RL; ZcytoR14

Immunogen: The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770

Conjugate: Unconjugated

Modification: Unmodified