IL1B Monoclonal Antibody - BT-MCA2770

IL1B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2770-50, BT-MCA2770-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase2 by this cytokine in the central nervous system is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Research Areas: Immunology

Target Protein: IL1B

Applications: IHC, ICC, FCM

Clonality: Monoclonal

Clone ID: 6F12D5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: IL1B

Immunogen: Purified recombinant fragment of human IL1B (AA: 117-269) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 30.7kDa

Synonyms: IL-1, IL1F2, IL1beta, IL1-BETA

GeneID: 3553

Research Use Only