IMP cyclohydrolase Monoclonal Antibody - BT-MCA0776

IMP cyclohydrolase Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0776-50, BT-MCA0776-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Research Areas: Epigenetics and nuclear signaling; Signal transduction; Metabolism

Target Protein: ATIC

Applications: WB

Reactivity: Human,Rabbit

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Bifunctional purine biosynthesis protein PURH

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P31939; Mouse: Q9CWJ9; Rat: O35567

Synonyms: ATIC; PURH; OK; SW-cl.86; Bifunctional purine biosynthesis protein PURH

GeneID: Human: 471

Research Use Only