Integrin Alpha6 Monoclonal Antibody - BT-MCA0785

Integrin Alpha6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0785-50, BT-MCA0785-100

Citations, Manuals and MSDS Available upon request.

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

Research Areas: Signal transduction; Stem cells; Developmental biology

Target Protein: ITGA6

Applications: WB, IF, ICC

Reactivity: Human,Mouse,Rat,Bovine,Dog,Pig

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Integrin alpha-6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P23229; Mouse: Q61739

Synonyms: ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD antigen CD49f

GeneID: Human: 3655

Research Use Only