IntegrinAlpha2 Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP04570-20, BT-AP04570-50, BT-AP04570-100
Citations, Manuals and MSDS Available upon request.
Background: ITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
Research Areas: Signal Transduction
Target Protein: ITGA2
Applications: WB, IHC-p, ELISA
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: Integrin alpha2 Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 129295
UniProt Accession: Human: P17301; Mouse: Q62469
Synonyms: ITGA2; CD49B; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b
GeneID: Human: 3673; Mouse: 16398
Research Use Only