IQGAP1 Rabbit pAb - A5679

IQGAP1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5679-20, A5679-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 189kDa

Observed Molecular Weight: 189kDa/189kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 8826

SWISS: P46940

Alternate Names: SAR1; p195; HUMORFA01; IQGAP1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:100 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Cell Adhesion, Endocrine Metabolism.

NCBI Alias: IQGAP1

Research Use Only