IRE1 Alpha Monoclonal Antibody - BT-MCA0787

IRE1 Alpha Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0787-50, BT-MCA0787-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Research Areas: Signal transduction

Target Protein: ERN1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Serine,threonine-protein kinase,endoribonuclease IRE1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O75460; Mouse: Q9EQY0

Synonyms: ERN1; IRE1; Serine; threonine-protein kinase; endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a

GeneID: Human: 2081

Research Use Only