Product Description

IRF-4 (Y294) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2659-50, BS2659-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Transcriptional activator. Binds to the interferon-stimμlated response element (ISRE) of the MHC class I promoter. Binds the immunoglobμlin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regμlatory element, followed by cooperative binding of BATF and IRF4 and activation of genes

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC, IF

Alternate Names: Interferon regμlatory factor 4, Lymphocyte-specific interferon regμlatory factor, LSIRF, Mμltiple myeloma oncogene 1, NF-EM5, IRF4, MUM1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 262-318 of Human IRF-4.

Dilution: IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IRF-4 (Y294) polyclonal antibody detects endogenous levels of IRF-4 protein.

Molecular Weight: ~ 52 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15306

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only