IRF3 Monoclonal Antibody - BT-MCA4335

IRF3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4335-50, BT-MCA4335-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

Research Areas: Immunology

Target Protein: IRF3

Applications: WB, IHC, FCM

Reactivity: Human, Mouse, Rat

Clonality: Monoclonal

Clone ID: 5G3E2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: IRF3

Immunogen: Purified recombinant fragment of human IRF3 (AA: 1-150) expressed in HEK293-6e cells supernatant.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 47.2kDa

UniProt Accession: Q14653

Synonyms: IIAE7

GeneID: 3661

Research Use Only