Product Description

IRF4 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66239-50, MB66239-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Transcriptional activator. Binds to the interferon-stimμlated response element (ISRE) of the MHC class I promoter. Binds the immunoglobμlin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regμlatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IHC

Alternate Names: MUM1, Interferon regμlatory factor 4, IRF-4, Lymphocyte-specific interferon regμlatory factor, LSIRF, Mμltiple myeloma oncogene 1, NF-EM5

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human IRF4. The exact sequence is proprietary.

Dilution: IHC (1/100 - 1/300)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of IRF4 protein.

Molecular Weight: ~ 51 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15306

Product: Mouse IgG. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Research Use Only