IRS2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-17345-60, E-AB-17345-120, E-AB-17345-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: IRS2
Target Synonym: Insulin receptor substrate 2; IRS 2; IRS-2; Irs2; IRS2
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9Y4H2
Background: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Concentration: 0.6 mg/mL
Immunogen: Synthetic peptide of human IRS2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-200, ELISA 1:2000-10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only