ISL1 Monoclonal Antibody - BT-MCA2604

ISL1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2604-50, BT-MCA2604-100

Citations, Manuals and MSDS Available upon request.

Background: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Research Areas: Stem cells, Cardiovascular, Neuroscience, Developmental biology

Target Protein: ISL1

Applications: IHC, ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1H9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ISL1

Immunogen: Purified recombinant fragment of human ISL1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 39kDa

UniProt Accession: P61371

Synonyms: Isl-1, ISLET1

GeneID: 3670

Research Use Only