Islet-1 Monoclonal Antibody - BT-MCA0789

Islet-1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0789-50, BT-MCA0789-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Research Areas: Stem cells; Cardiovascular; Neuroscience; Developmental biology

Target Protein: ISL1

Applications: WB, IF, ICC, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Insulin gene enhancer protein ISL-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P61371; Mouse: P61372

Synonyms: ISL1; Insulin gene enhancer protein ISL-1; Islet-1

GeneID: Human: 3670

Research Use Only