Product Description

Islet 1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11125-50, MB11125-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P61371

Host: Rabbit

Reactivity: Human, Rat

Applications: WB,IHC-P,IP

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Islet 1 in K562, rat BrainLysates using Islet 1 antibody.

Bioworld Molecular Weight: Calculated MW: 39 kDa; Observed MW: 39 kDa

Specificity: IgG

Alternative Name: ISL1; Insulin gene enhancer protein ISL-1; Islet-1

Immunogen: Recombinant protein of human Islet 1

Conjugate: Unconjugated

Modification: Unmodified