ITGB4 Monoclonal Antibody - BT-MCA4012

ITGB4 Monoclonal Antibody Sizes: 50μL, 100μL Catalogue Number: BT-MCA4012-50, BT-MCA4012-100 Citations, Manuals and MSDS Available upon request. Background: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.


Research Areas: Signal Transduction Target Protein: ITGB4 Applications: IHC, FCM Reactivity: Human Clonality: Monoclonal Clone ID: 10B10D5 Host: Mouse Isotype: Mouse IgG1 Full Product Name: ITGB4 Immunogen: Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. Coli. Storage: 4°C|-20°C for long term storage Formulation: Purified antibody in PBS with 0.05% sodium azide. Molecular Weight (Da): 202kDa UniProt Accession: P16144 Synonyms: CD104 Research Use Only