JAK3 Monoclonal Antibody - BT-MCA0798

JAK3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0798-50, BT-MCA0798-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Research Areas: Signal transduction; Cancer; Epigenetics and nuclear signaling

Target Protein: JAK3

Applications: WB, IF, ICC, FCM, ELISA

Reactivity: Human,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Tyrosine-protein kinase JAK3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P52333; Mouse: Q62137

Synonyms: JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK

GeneID: Human: 3718; Mouse: 16453

Research Use Only