Product Description

K-Ras Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26725-50, RA26725-100

Citations, Manuals and MSDS Available upon request.

Background: KRAS proto-oncogene, GTPase (KRAS) Homo sapiens This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: GTPase KRas (K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3845

Protein MW (KDa): 22

SWISS: P01116

Source: Rabbit

Research Use Only