KAT6B Monoclonal Antibody - BT-MCA2375

KAT6B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2375-50, BT-MCA2375-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

Research Areas: Epigenetics and nuclear signaling

Target Protein: KAT6B

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8C8D12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: KAT6B

Immunogen: Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 231.4kDa

UniProt Accession: Q8WYB5

Synonyms: qkf, MORF, MOZ2, GTPTS, MYST4, ZC2HC6B, querkopf

GeneID: 23522

Research Use Only