Product Description

KCNT1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26622-50, RA26622-100

Citations, Manuals and MSDS Available upon request.

Background: potassium sodium-activated channel subfamily T member 1 (KCNT1) Homo sapiens Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 57582

Protein MW (KDa): 140

SWISS: Q5JUK3

Source: Rabbit

Research Use Only