KDR Monoclonal Antibody - BT-MCA2943

KDR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2943-50, BT-MCA2943-100

Citations, Manuals and MSDS Available upon request.

Background: KDR has also been designated as VEFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Research Areas: Cardiovascular

Target Protein: KDR

Applications: ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4B4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: KDR

Immunogen: Purified recombinant extracellular fragment of human KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 152kDa

UniProt Accession: P35968

Synonyms: FLK1, CD309, VEGFR, VEGFR2

GeneID: 3791

Research Use Only