KDR Monoclonal Antibody - BT-MCA4633

KDR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4633-50, BT-MCA4633-100

Citations, Manuals and MSDS Available upon request.

Background: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Research Areas: Cardiovascular

Target Protein: KDR

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3C11A5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: KDR

Immunogen: Purified recombinant fragment of human KDR (AA: 1225-1356) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 151.5kDa

UniProt Accession: P35968

Synonyms: FLK1, CD309, VEGFR, VEGFR2

GeneID: 3791

Research Use Only